Age-related macular degeneration
PBM for non-exudative age-related macular degeneration Cochrane review
Henein C, Steel DH. Cochrane Database of Systematic Reviews. 2021.
A Cochrane review found uncertainty about whether PBM slows progression of non-exudative AMD.
Evidence grade
low
Effect direction
unclear
Panel relevance
not-panel-replicable
Key findings
- The review included two published RCTs with 90 participants and 106 eyes.
- There was no evidence of a meaningful clinical difference in best-corrected visual acuity at 12 months.
- The authors called for better-designed trials powered for effectiveness and safety.
Protocol details
| Wavelengths | Not reported nm |
|---|---|
| Irradiance | Not reported mW/cm2 |
| Fluence | Not reported J/cm2 |
| Session time | Not reported minutes |
| Frequency | Ophthalmology-device specific |
| Duration | Ophthalmology-device specific |
| Treatment area | Eyes/retina |
| Device type | Specialized ophthalmic PBM systems |
Caveats
- Very low to low certainty evidence.
- Consumer panel eye exposure should not be encouraged.