Orthodontic pain

Low-level laser therapy for orthodontic pain

Dental evidence on LLLT for pain after orthodontic force, separators, and archwires.

Study count

Cited reviews include 20 RCTs and a diode-laser review of 14 RCTs with 659 participants.

Evidence grade

low

Panel relevance

not-panel-replicable

Bottom line

This is a dental-professional category and should not be used to sell red light panels.

Consensus: LLLT appears to reduce short-term orthodontic pain, but trial quality is often weak.

What the studies found

  • A 2017 review found reductions in spontaneous and chewing pain after orthodontic force.
  • A 2015 review found diode LLLT reduced orthodontic pain by 39% versus placebo.
  • Both reviews emphasized methodological weaknesses.

Dosage and timing

WavelengthsNot settled nm
IrradianceNot settled
FluenceNot settled
Session timeDental protocol-specific.
FrequencyTimed around orthodontic force or dental procedures.
DurationPain outcomes commonly at 24 and 72 hours.
TimingProcedure-timed.
Treatment areaDental/orthodontic targets.
Device typesDiode and other dental low-level lasers.
NotesHigh risk of bias is common.
  • Timing is tied to orthodontic procedures.
  • No panel-relevant protocol exists.
  • Dental professionals should choose protocol and device.

Caveats

  • Orthodontic pain protocols are intraoral/dental, not home panel protocols.
  • Evidence quality limits confidence.

Cited peer-reviewed sources

meta-analysis 20 included studies Evidence: low; direction: positive Panel relevance: not-panel-replicable Wavelengths: Not reported Dose/timing: Dental procedure-specific / Outcomes commonly assessed at 24 and 72 hours Area: Orthodontic dental targets Device: Dental low-level laser therapy Source

Deana NF, Zaror C, Sandoval P, et al. Pain Research and Management. 2017.

A meta-analysis found LLLT reduced spontaneous and chewing pain after orthodontic force, but evidence quality was poor.

Source

meta-analysis 14 included studies Evidence: low; direction: positive Panel relevance: not-panel-replicable Wavelengths: Not reported Dose/timing: Dental procedure-specific / Short-term orthodontic pain windows Area: Orthodontic dental targets Device: Diode low-level laser therapy Source

Ren C, McGrath C, Yang Y. Lasers in Medical Science. 2015.

A diode LLLT meta-analysis found reduced orthodontic pain versus placebo, but methodological weaknesses were substantial.

Source

Last reviewed: 2026-06-15